Sphingosine-1-Phosphate: Boon and Bane for the Brain

Sphingosine-1-phosphate: boon and bane for the brain.

Sphingosine-1-phosphate (S1P), an evolutionary conserved bioactive lipid, is essential for brain development, but might also exert detrimental effects in terminally differentiated post-mitotic neurons. Its concentration in the brain is tightly regulated by specific kinases and phosphatases, and mainly by the S1P degrading enzyme, S1P-lyase (S1PL). The role of S1P in neurons was initially studie...

Calotropis boon or bane?

The herbal medicine occupy distinct position right from ancient period. The plant Calotorpis procera is known by different name in different part of world like French cotton, Alarka, or Madar, Rooster tree, and Widuri. The plant is poisonous can lead to blindness if its juice is put in to the eyes. The same plant is used for Ayurvedic medicines. The medicinal properties like Calotropin isolated...

Tax Competition : Bane or Boon ?

Online voting: Boon or bane for democracy?

Estonia is the only country in the world where all voters can vote online in national elections. In the 2015 election, 31% of voters did so. This paper discusses the sociology and politics of online voting in Estonia. I first show that online voting is a partisan project. Liberal, conservative, and social democratic parties support online voting as a way of modernizing the electoral system, whi...

E-hrm: a Boon or Bane

Nothing is constant but change holds true in this ever transforming business world, technological advancements are one of the powerful driving forces. It has redesigned the way we live, communicate, work and also the way business is conducted. The technology and digitized business communications have enhanced and reformed various organizational activities. The impact of this IT revolution can b...